Used for blood pressure or fluid retention.
Examples: loop diuretics, thiazides.
Why risky: They can alter fluid and electrolyte balance, stressing the kidneys.

5. Certain antivirals

Used for HIV, herpes, or hepatitis.
Examples: tenofovir (older formulations), acyclovir (in high doses).
Why risky: They can form crystals in the kidneys or reduce kidney function.

6. Chemotherapy drugs

Some cancer treatments are known for kidney toxicity.
Examples: cisplatin, methotrexate.
Why risky: They can damage kidney cells.

7. Lithium

Used for bipolar disorder.
Why risky: Can cause long-term kidney damage if levels are not carefully monitored.

8. Herbal supplements with unknown or toxic ingredients

Examples: aristolochic acid–containing herbs, very high-dose turmeric supplements, “fat burner” or “detox” pills.
Why risky: Many contain substances that strain or poison the kidneys.

✅ Important notes

• These medications are NOT always dangerous — doctors prescribe them safely every day.

• Kidney damage usually happens with high doses, long-term use, dehydration, interactions, or in people who already have kidney problems.

• Never stop prescribed medication without talking to a professional.